Booster shot risk

Doctors still recommend vaccinations, including for babies as young as six months old, but more and more scientists, including Jean-Marc Sabatier, warn of the damage caused by repeated vaccinations to the immune system and the body. doing.

The unwanted effects of vaccines against Covid-19 have not yet been explicitly listed by WHO and health authorities. That is why the European Medicines Agency (EMA) and French health authorities recommend vaccinations including babies from 6 months of age, giving her third and her fourth boosters to the most vulnerable patients. Recommended.
But more and more scientists are warning against repeated vaccinations. In April 2022, the medical journal Cureus stated, “The adverse event profile of these vaccines is not well established. Neurological complications are increasingly reported. One of these identified complications is is an immune-mediated inflammatory polyneuropathy that affects peripheral nerves and neurons.” In other words, repeated vaccinations have a negative impact on the immune system and the body.

“Fundamental Discovery”

“One of these side effects is immune-mediated inflammatory polyneuropathy,” the journal wrote. It is further classified as acute or chronic based on the appearance and duration of symptoms. ”
Months later, the EMEA acknowledged that vaccine boosters could cause immune response problems and called on individual states not to ramp up booster campaigns.
These recommendations are provided rather late. In April 2020, Jean-Marc Sabatier* announced a “fundamental discovery” made a month earlier with virologists in Wuhan (China). Even in the absence of the SARS-CoV-2 virus, a malfunction occurs called the renin-angiotensin system (RAS).
Infodujour.fr published an interview with the scientist on December 21, 2020. Or the story of a fundamental French discovery that could change the understanding and treatment of this apparently mysterious disease.

oil on fire

In this interview conducted by Dr. Jean-Michel Wendling, Scientific Advisor of infodujour.fr, Jean-Marc Sabatier reveals that the ‘real’ culprit of Covid-19 is the renin-angiotensin system (RAS) and SARS-CoV- 2 is oil for fire. In fact, even in the absence of a virus, so-called “Covid-19-like” diseases can occur when RAS goes out of control and overworked.
In March 2020, Jean-Marc Sabatier had identified extraordinary similarities between the consequences of SARS-CoV-2 infection and the failure of this “critical” system in the human body. . These analogies are reported in a scientific publication co-authored by Dr. Emmanuelle Faucon and her other collaborators, her Prof. Zhijian Cao, director of the Wuhan Institute of Virology (China), and her Prof. Yingliang Wu. it was done.
Upon infection with SARS-CoV-2, the virus binds to ACE2 (angiotensin-converting enzyme 2) receptors on target cells and normally degrades the angiotensin 2 hormone. This SARS-CoV-2 binding to her ACE2 receptor prevents normal degradation. Concentrations of angiotensin 2 increase, overactivating its cellular target, her AT1R receptor.

all over the human body

what is that? Overactivated AT1R receptors are highly harmful to the human body through a highly toxic storm of released cytokines (TNF-alpha, interferon-gamma, interleukin-6, interleukin-1-beta, etc.) is. These mediators are involved in the progression to severe (even fatal) forms of Covid-19.
The renin-angiotensin system (RAS) is an essential hormonal/physiological system found throughout the human body, including lungs, kidneys, spleen, liver, pancreas, intestine, heart, brain, testicles and prostate, uterus and ovaries, and adrenal glands. Cells of the auditory system, eyes, blood vessels, and the “innate” immune system (circulating monocytes, macrophages, dendritic/antigen-presenting cells, granulocytes, mast cells, and natural killer cells). RAS regulates ‘innate’ immunity (an ‘immediate’ non-specific response to pathogens) and various microbiota, including the gut microbiota.

Covid-19 without a virus?

RAS contributes to Covid-19 disease through overactivation of its ‘harmful’ receptor, AT1R. This hyperactivated receptor primarily induces vasoconstriction/hypertension, inflammation, oxidative stress, hypoxia, angiogenesis, thrombus formation, nitric oxide depression, hypertrophy, and organ fibrosis.
This “harmful” effect includes hypertension, atherosclerosis, hypertrophy (heart, blood vessels), fibrosis (heart, lung, kidney, liver), heart failure, kidney and lung damage (acute respiratory distress syndrome, asthma, etc.). ), anosmia (loss of smell), anorexia (loss of taste), neuropathy/memory impairment, diarrhea, intestinal and vascular inflammation, lipid metabolism disorders, obesity and glucose metabolism (diabetes), thrombosis/clotting Disorders, skin and testicular damage. In addition, ‘deregulated’ RAS has been shown to affect the central nervous system, cell proliferation and adhesion, and ‘innate’ immunity.
Our in-depth knowledge of the physiological impact of ‘runaway’ RAS has enabled us to explain, understand and predict all Covid-19 diseases associated with SARS-CoV-2 infection.

Hope for Vitamin D

How can this harmful trend be stopped? As explained by Jean-Marc Sabatier and Emmanuelle Faucon in March 2020, vitamin D is at the heart of all hope. The disease (and symptoms) of Covid-19 may be counteracted and treated by molecules that can “brake” RAS hyperactivation. Several known molecules are ‘brakes’ for overactivated RAS (dexamethasone, melatonin, thymoquinone, sartans, enzyme conversion inhibitors, ivermectin, quercetin, aliskiren, etc.). Of these molecules, vitamin D is (even more!) of particular importance as it is the fuel for all cells of the immune system. These immune cells, as well as other cell types, require vitamin D (calcidiol or calcitriol) to act especially against microorganisms like SARS-CoV-2. It is easy to administer orally and has a low cost. Essential for people who are or are deficient in vitamin D (take cholecalciferol or vitamin D3, or dedrogyl (calcidiol) in emergencies for ultra-quick action). Such vitamin D3 (or even vitamin D2) supplementation is especially recommended this fall when viral circulation is high, considering vitamin D deficiency/deficiency in the majority of the population.

*Jean-Marc Sabatier, Research Director, CNRS, PhD in Cell Biology and Microbiology, HDR in Biochemistry. Editor-in-chief of the international scientific journals “Coronaviruses” and “Infectious Disorders – Drug Targets”. He speaks by his own name here.