Stanislas Cohort Fifth Visit

A jewel of Lorraine medical research, the Stanislas cohort is one of the largest family cohorts (involving several generations) in the world.

Over the past two decades, studies of data from 4,295 healthy volunteers have enabled us to advance our knowledge of cardiovascular risk factors, more specifically the role of genetics and environmental influences.

Volunteer recruitment started in 1993

The work done by the Stanislas cohort has given international reach with the publication of over 100 scientific papers and implementation of research protocols. The seriousness and success of these studies depend on updating and follow-up of data collected from volunteers. Therefore, meet with them regularly to share information on the research carried out by the entire CIC-P team (Centre d’Investigation Clinique Plurithématique – Inserm, CHRU and research organizations supervised by the University of Lorraine). is important. Make plans for future meetings.

Fifth visit to improve knowledge of cardiovascular risk

This will take place on October 15, 2022 at the Nancy School of Medicine in the presence of the coordinators of the Stanislas cohort, Prof. Nicolas Gilles and Prof. Jean-Marc Boivin, Cardiologist and General Practitioner respectively, accompanied by the entire research team. To do. This fifth visit will bring back to the public what has been achieved since his fourth visit, which began in 2011.

• “At-Risk Dietary Profiles” by Generation and Gender
• Genetics and heritability in cardiovascular risk
• Abdominal obesity and arteriosclerosis
• Hypertension and primary care
• Risk of prediabetes and type II diabetes
• A new risk prediction tool for heart failure e’VM algorithm

The only cohort in the world

A major strength of the Stanislas cohort is the long-lasting follow-up of its constituent volunteer groups. For nearly 20 years, thanks to documented medical visits, they have composed a unique profile that is unique in the world. attended four in-depth medical visits completed by a targeted questionnaire that collected Her fourth visit, performed by Nancy’s CIC-P, repeated the tests and tests performed in the previous year and was completed by other procedures such as blood and urine samples, an electrocardiogram, and an echocardiogram. Did. The Stanislas cohort was from the Nancy region and had no chronic illnesses at the time of recruitment. A family must consist of two parents and at least two of his biological children.

Cardiovascular disease (Source: Haute Autorité de Santé, March 2021)

Cardiovascular disease is the second leading cause of death in France, with large social and regional disparities. It is the leading cause of death for women and those over the age of 65. Its frequency is associated with an increase in risky behavior. Examples include poor diet, lack of physical activity, sedentary lifestyle, smoking or alcohol abuse, and exposure to stress. These behavioral traits can lead to hypertension, hyperglycemia, hyperlipidemia, and excess weight. The challenge is to reduce cardiovascular morbidity and mortality in the French population by:

• Better identification and management of people at cardiovascular risk, including low-risk patients. By offering non-drug strategies to support lifestyle changes,
• drug strategy, if appropriate, adapted to therapeutic goals according to level of cardiovascular risk, whether primary or secondary prevention;
• Patient engagement and adherence to proposed treatment strategies is facilitated by shared medical decisions thanks to the integration of the best possible evidence and adapted communication tools.