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The Russian Sputnik V vaccine has a 91.6% efficacy against COVID-19, a study based on a Phase 3 trial said.

The results of this study suggest that Sputnik V is one of the best vaccines, along with Pfizer / BioNTech and Modenajab, which have reported efficacy of over 90%.

Representative image. AP

Russian Sputnik V vaccine is 91.6% effective against symptomatology COVID-19 According to the results published in Lancet On Tuesday, an independent expert said Moscow had eased concerns about transparency over the already deployed jabs.

Named after a Soviet-era satellite, Sputnik V was approved in Russia months before the results of its final clinical trials were announced, leading to skepticism from experts.

However, a new analysis of data from 20,000 participants in the Phase 3 trial suggests that two doses provide more than 90% efficacy for symptomatology. COVID-19 ..

“The development of the Sputnik V vaccine has been criticized for its unsightly speed, dicing and lack of transparency,” said Ian Jones of the University of Reading and Polly Roy of the London School of Hygiene and Tropical. An independent lancet commentary by. medicine.

“But the results reported here are clear and demonstrate the scientific principles of vaccination, which means that another vaccine can participate in the fight to reduce the incidence. COVID-19 .. “

The results suggest that Sputnik V is one of the best vaccines, along with Pfizer / BioNTech and Modanajab, which have reported over 90% efficacy.

Russia has already launched a mass vaccination campaign for citizens over the age of 18 ahead of the results of the Phase 3 trial.

Several countries around the world have already registered Sputnik V, according to the Russian Direct Investment Fund, which supported the development of vaccines, including Belarus, Venezuela, Bolivia and Algeria.

In January, Chancellor Angela Merkel said Germany provided Russia’s assistance in the development of Sputnik V in Moscow after the Russian authorities said they had applied for registration with the European Union.

“Global response”

In this study, 14,964 participants in the vaccine group and 4,902 participants in the placebo group were given two jabs at 21-day intervals.

participant is COVID-19 At the time of enrollment in the study, at the time of the second dose, and if symptoms are reported thereafter.

16 cases with symptoms from the second time COVID-19 Confirmed in the vaccine group, 62 cases were reported in the placebo group, with efficacy equivalent to 91.6%.

However, the authors stated that efficacy is calculated only in symptomatic cases and further research is needed to assess how it affects asymptomatic disease.

They added that the full duration of protection is still unknown, as the follow-up period was about 48 days from the first dose. The trial is underway and will employ a total of 40,000 people.

Sputnik V uses two different disarmament strains of adenovirus, the common cold-causing virus, as vectors to deliver vaccine doses.

Developers say that using different adenovirus vectors for booster vaccination may help generate a stronger response by minimizing the risk of the immune system developing resistance to the first vector. Said.

Alexander Edwards, an associate professor of biomedical technology at the University of Reading, said the study may help provide evidence of the theory of this immune response.

“A pandemic means” everything, “and the only way to address global issues is to share data, science, technology, and medicine.

This vaccine has the advantage that it can be stored at normal refrigerator temperatures rather than the sub-zero conditions required for other vaccines.

The Russian Sputnik V vaccine has a 91.6% efficacy against COVID-19, a study based on a Phase 3 trial said.

Source link The Russian Sputnik V vaccine has a 91.6% efficacy against COVID-19, a study based on a Phase 3 trial said.

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